Browsing Department of Mathematics by Subject "Signaling pathway"

Now showing items 1-1 of 1

Validation of signaling pathways: case study of the p16-mediated pathway

Akçay, Nimet İlke; Bashirov, Rza; Tüzmen, Şükrü (Journal of Bioinformatics and Computational Biology, World Scientific Publishing, 2015)

p16 is recognized as a tumor suppressor gene due to the prevalence of its genetic inactivation in all types of human cancers. Additionally, p16 gene plays a critical role in controlling aging, regulating cellular senescence, ...