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Pruning Techniques in Łukasiewicz Logics
(Budapest Tech, 2025) Basbous, Raed; Nagy, Benedek; Tajti, Tibor
Short circuit evaluations and related pruning techniques play important roles in logic, artificial intelligence and computer science, especially, in software engineering, decision-making and hardware design. Here, we consider a well-known and widely applied fuzzy logic system, the & Lstrok;ukasiewicz logic. We present and prove various pruning techniques to make the evaluations of logical formulas faster and more efficient, by cutting those branches of the formula tree that have no influence on the result at the root. Complex examples show the efficiency of our pruning techniques, which are used to do the evaluation of formulas faster in & Lstrok;ukasiewicz logic. This logic is appropriate for various engineering applications related to fuzzy technology and decision making; therefore, our results are important for fast evaluation.
Virtual-reality-based methodology for modelling and verifying shop floor control systems
(Sage Publications Ltd, 2010) Manesh, H. F.; Hashemipour, M.
The design and development of shop floor control systems (SFCSs) in automated manufacturing plants requires careful thought to ensure that the manufacturing system successfully satisfies the demands of today's competative marketplace. This paper presents a methodology for the development of SFCSs that is based on virtual reality (VR) in order to assist the system designer at each stage of development. Exploiting VR helps the user to collect valid information quickly and in a correct form by putting the user and the information support elements in direct relation with the operation of the system in a more realistic environment. A VR-SFCS prototype tool is designed as a software system to realize the features outlined in each phase of the methodology. A set of rules and a knowledge base is appended to the methodology to remove any inconsistency that could arise between the material and the information flows during the development. A novel environment for matching the physical and the informational model domains is recommended in order to delineate the system requirements specification.
Development and In vivo Evaluation of Atomoxetine Hydrochloride ODMTs in a Nicotine-induced Attention Deficit Hyperactivity Disorder (ADHD) Model in Rats
(Springer, 2024) Atalay, Ozbeyen; Ozyilmaz, Emine Dilek; Onal, Deniz; Pehlivanoglu, Bilge; Comoglu, Tansel
The current study aimed to evaluate the efficacy of orally administered rapid mini-tablets containing atomoxetine hydrochloride (ODMT) relative to the conventional capsule formulation of atomoxetine hydrochloride (ATO). To mask the bitter taste of ATO and render it more palatable for pediatric administration in individuals with Attention Deficit Hyperactivity Disorder (ADHD), an inclusion complex of ATO with beta-cyclodextrin (beta-CD) was synthesized. The ODMT and conventional capsule ATO formulations were administered orally to a cohort of ADHD rat pups born to nicotine-exposed dams, facilitating an in vivo efficacy assessment. Behavioral assays, including the open field test, novel object recognition test, and Barnes maze test, were conducted pre- and post-administration of the therapeutics. The outcomes suggested that the ODMT formulation, incorporating ATO-beta-CD inclusion complexes, shows promise as a viable alternative to the capsule form of ATO. Conclusively, the preparation of the ATO-beta-CD complexes and ODMTs leveraged a factorial experimental design, with the animal model being subjected to nicotine-induced hyperactivity to provide a unique evaluative framework for the ODMT formulation under development.
Flexoelectric fluid membrane vesicles in spherical confinement
(Iop Publishing Ltd, 2020) Abtahi, Niloufar; Bouzar, Lila; Saidi-Amroun, Nadia; Muller, Martin Michael
The morphology of spherically confined flexoelectric fluid membrane vesicles in an external uniform electric field is studied numerically. Due to the deformations induced by the confinement, the membrane becomes polarized resulting in an interaction with the external field. The equilibrium shapes of the vesicle without electric field can be classified in a geometrical phase diagram as a function of scaled area and reduced volume (Kahraman O. et al., EPL, 97 (2012) 68008; Kahraman O. et al., New. J. Phys., 14 (2012) 095021). When the area of the membrane is only slightly larger than the area of the confining sphere, a single axisymmetric invagination appears. A non-vanishing electric field induces an additional elongation of the confined vesicle which is either perpendicular or parallel depending on the sign of the electric field parameter. Higher values of the surface area or the electric field parameter can reduce the symmetry of the system leading to more complex folding. We present the resulting shapes and show that transition lines are shifted in the presence of an electric field. The obtained folding patterns could be of interest for biophysical and technological applications alike.
Evaluation of medication adherence in hypertensive patients and influential factors
(Professional Medical Publications, 2018) Boratas, Selma; Kilic, Hulya Firat
Objective: This study aims to evaluate medication adherence in hypertensive patients and to identify the influential factors. Methods: This descriptive, cross-sectional study included a total of 147 hypertensive patients who were admitted to Akdogan Health Center between December 2016 and February 2017. The Descriptive Data Form and Medication Adherence Self-Efficacy Scale were used as the data collection tools. Results: The mean Medication Adherence Self-Efficacy Scale score was found to be 70.29 +/- 8.52. Age, duration of HT, the frequency of follow-up visit for HT, the status of taking medication regularly, the frequency of blood pressure measurement and the status of alternative method use were found to be effective in medication adherence. Conclusions: Our study results suggest that medication adherence is good in patients with hypertension ( HT). Factors which are effective in medication adherence should be taken into consideration, when evaluating the medication adherence in patients with HT.