Synthesis, characterization and biocompatibility studies on chitosan-graft-poly(EGDMA)

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dc.contributor.authorAdali, Terin
dc.contributor.authorYilmaz, Elvan
dc.date.accessioned2026-02-06T18:37:20Z
dc.date.issued2009
dc.departmentDoğu Akdeniz Üniversitesi
dc.description.abstractPoly(ethylene glycol dimethacrylate), poly(EGDMA), was grafted onto chitosan by using a redox initiation system. Chitosan-graft-poly(EGDMA) products were characterized by DSC, TGA, FTIR and XRD techniques. Chitosan-graft-poly(EGDMA) was found to be enzymatically degradable in aqueous solutions of lysozyme, lipase and a mixture of a-amylase and protease. The biocompatibility of chitosan-graft-poly (EGDMA) with 871% grafting yield was investigated by studying its cytotoxicity, sensitization, irritation, acute systemic toxicity and hemolytic activity. The results of biocompatibility experiments showed that the product can potentially be used for external intervention devices on bone and other tissue. (C) 2009 Published by Elsevier Ltd.
dc.identifier.doi10.1016/j.carbpol.2008.12.017
dc.identifier.endpage141
dc.identifier.issn0144-8617
dc.identifier.issn1879-1344
dc.identifier.issue1
dc.identifier.scopus2-s2.0-67349133469
dc.identifier.scopusqualityQ1
dc.identifier.startpage136
dc.identifier.urihttps://doi.org/10.1016/j.carbpol.2008.12.017
dc.identifier.urihttps://hdl.handle.net/11129/12426
dc.identifier.volume77
dc.identifier.wosWOS:000266422300020
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Sci Ltd
dc.relation.ispartofCarbohydrate Polymers
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260204
dc.subjectBiocompatibility
dc.subjectBiodegradability
dc.subjectCerium(IV)
dc.subjectCopolymerization
dc.subjectDimethacrylate
dc.titleSynthesis, characterization and biocompatibility studies on chitosan-graft-poly(EGDMA)
dc.typeArticle

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