The effects of dietary intervention with turmeric on lipid profile and anthropometric indices in overweight/ obese women with hyperlipidemia: a randomized controlled clinical trial

Abstract

Background and Objective: The objective of this trial was to evaluate the effects of turmeric on blood lipids and body weight loss in overweight/obese women with hyperlipidemia. Methods and Study Desing: In this randomized controlled trial, overweight/obese hyperlipidemic women (BMI>25 kg/m2) were randomly divided into 2 groups as turmeric (n=35; 4 g/d) and control (n=35) groups for 8 weeks. The subjects included in the turmeric and control groups adhered to a medical nutrition therapy. Serum lipid profile and anthropometric data were measured at the beginning and again at the end of the study. Results: After 8 weeks of dietary intervention, both turmeric and control groups showed significant decreased in total cholesterol (-55.66 versus -53.06 mg/dl), LDL-C (-35.70 versus -35.91 mg/dl) and TG (-44.34 versus -42.03 mg/dl), respectively (p<0.01). Body weight (-5.05 versus -4.91 kg), BMI (-1.88 versus -1.84 kg/m2), body fat ratio (-4.02 versus -3.30%) and waist circumference (-4.70 versus -3.74 cm) were also significantly decreased after dietary intervention in both groups, respectively (p<0.001). No significant difference was found in the reductions of total cholesterol, LDL-C, TG concentrations or in the reductions of body weight, BMI and waist circumference between the turmeric and control groups (p>0.05). Conclusions: Further randomized controlled trials with longer supplementation durations are needed for a stronger assessment of the lipid-modulating properties of turmeric. © 2022 Mattioli 1885. All rights reserved.