Reaction Systems for Modeling and Validation of Biological Signaling Pathways: G1/S Checkpoint of the Cell Cycle

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dc.contributor.authorAkcay, Nimet Ilke
dc.contributor.authorNagy, Benedek
dc.contributor.authorTuzmen, Sukru
dc.date.accessioned2026-02-06T18:53:11Z
dc.date.issued2021
dc.departmentDoğu Akdeniz Üniversitesi
dc.description.abstractReaction Systems modeling is a compact, discrete, and qualitative modeling method for dynamic systems, including biochemical systems. In this paper, the G1/S checkpoint of the human cell cycle is modeled by Reaction Systems. This specific checkpoint is important since it plays role in tumor formation. Modeling discrete dynamic systems with Reaction Systems has many advantages over other modeling tools, i.e., the model is very small, deterministic and it is easy to use in simulations without any specific software package.
dc.identifier.doi10.12700/APH.18.6.2021.6.1
dc.identifier.endpage23
dc.identifier.issn1785-8860
dc.identifier.issue6
dc.identifier.orcid0000-0001-5096-069X
dc.identifier.scopus2-s2.0-85109033343
dc.identifier.scopusqualityQ1
dc.identifier.startpage7
dc.identifier.urihttps://doi.org/10.12700/APH.18.6.2021.6.1
dc.identifier.urihttps://hdl.handle.net/11129/15865
dc.identifier.volume18
dc.identifier.wosWOS:000658289300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBudapest Tech
dc.relation.ispartofActa Polytechnica Hungarica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260204
dc.subjectCell Cycle
dc.subjectG1/S checkpoint
dc.subjectReaction Systems
dc.subjectSimulation
dc.titleReaction Systems for Modeling and Validation of Biological Signaling Pathways: G1/S Checkpoint of the Cell Cycle
dc.typeArticle

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