Synthesis, Characterization and Application of Cellulose Based Nano-Biocomposite Hydrogels

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dc.contributor.authorSaber-Samandari, Samaneh
dc.contributor.authorSaber-Samandari, Saeed
dc.contributor.authorGazi, Mustafa
dc.contributor.authorCebeci, Fevzi C.
dc.contributor.authorTalasaz, Emad
dc.date.accessioned2026-02-06T18:46:59Z
dc.date.issued2013
dc.departmentDoğu Akdeniz Üniversitesi
dc.description.abstractNano-hydroxyapatite/cellulose-graft-polyacrylamide biocomposite hydrogels of different molar ratios were prepared to examine their potential application as a carrier for colon targeted drug delivery in vitro. The particle size of the synthesized nano-hydroxyapatite was found to be 122nm. The swelling behavior of the composite hydrogels was observed in acidic and basic aqueous solution that simulated lower small intestine, colon and stomach fluids. The hydrogel could be applied in drug-delivery systems and acetylsalicylic acid was used as a model compound to test such a possibility. Finally, the synthesized biocomposite hydrogels with the 96.97% maximum encapsulation and 85.67% release efficiency in the basic medium were found to be a suitable candidate to carry and release of colon-targeted drugs.
dc.identifier.doi10.1080/10601325.2013.829362
dc.identifier.endpage1141
dc.identifier.issn1060-1325
dc.identifier.issn1520-5738
dc.identifier.issue11
dc.identifier.orcid0000-0003-1975-7436
dc.identifier.orcid0000-0002-3118-0038
dc.identifier.scopus2-s2.0-84884842177
dc.identifier.scopusqualityQ2
dc.identifier.startpage1133
dc.identifier.urihttps://doi.org/10.1080/10601325.2013.829362
dc.identifier.urihttps://hdl.handle.net/11129/14166
dc.identifier.volume50
dc.identifier.wosWOS:000324611000006
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofJournal of Macromolecular Science Part A-Pure and Applied Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260204
dc.subjectacrylamide
dc.subjectcellulose
dc.subjectcomposite
dc.subjecthydrogel
dc.subjectnano-hydroxyapatite
dc.titleSynthesis, Characterization and Application of Cellulose Based Nano-Biocomposite Hydrogels
dc.typeArticle

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